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Its suppression through LAN exposure is hypothesized to facilitate estrogen-dependent carcinogenesis 21

Endothelial function and oxidative stress in cardiovascular diseases

Studies using p16-3MR transgenic mice demonstrated that removing senescent cells after doxorubicin treatment reduced inflammatory factors in circulation, promoted hematopoietic progenitor cell recovery, and prevented cardiac dysfunction [28]

S2CID 258439047

The math is clean and the measurements are straightforward