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Accordingly, monitoring during GLP-1 receptor agonist therapy should include functional assessments (eg, handgrip strength, chair-stand performance, and gait speed), along with consideration of bone health in high-risk patients, particularly older adults, those with frailty, or those experiencing rapid weight loss

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The future directions and challenges of new small-molecule GLP-1R agonists, such as danuglipron, are multifaceted

In summary, Arakawa M, et al

doi: 10.1016/j.molmet.2020.101102 11 MllerTDFinanBBloomSRD'AlessioDDruckerDJFlattPRet al