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In clinical trials, retatrutide was generally introduced with a low starting dose and increased gradually over time

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It is available only through enrollment in clinical trials

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Dosing gabapentin at night takes advantage of its sedation profile and avoids daytime dizziness that would compound spironolactone's orthostatic effect

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However, Wegovy is not recommended for people with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), so your medical history should always be reviewed before treatment

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