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The trade-offs are that it is approved only for short-term use, it can raise heart rate and blood pressure, and weight tends to return after stopping
These symptoms make sense biologically, based on how GLP-1 drugs can engage and modulate dopamine-producing neurons in the brains ventral tegmental area (VTA), a region that influences peoples moment-to-moment motivation for motor, cognitive, and complex executive behavior, the doctors wrote
Results vary from person to person, and the medication is always used alongside diet, exercise, and medical supervision
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Injectable forms remain the most effective and reliable delivery method
These backdoor indications may gradually improve access for Medicare patients living with obesity and the above related comorbidities, Knapp says
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