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A 2025 study published in JAMA Network Open found that most patients with obesity discontinue GLP-1 therapy within a year, particularly those without type 2 diabetes 1

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For this reason, we typically recommend a short series of injections, often beginning with a package of three treatments or more, depending on the therapy and your individual health goals

A human lens model of cortical cataract: Ca2+-induced protein loss, vimentin cleavage and opacification