With how little we know about the experimental compound, its long term effects, potential negative side effects, etc., I do think it would be irresponsible to recommend it to others, especially athletes one is coaching
Di Cesare Mannelli L, Ghelardini C, Calvani M, et al
These changes enhance its stability and result in a significantly prolonged half-life of 20-30 hours, compared to the much shorter duration of other IGF-1 versions
Nature 546 (7657), 254258
For Wegovy specifically, the cardiovascular indication added in March 2024 (based on SELECT trial, Lincoff et al
The same mechanism may explain why the risk appears highest in the first year of therapy when metabolic improvements are most rapid and why the signal seems stronger with more potent agents