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65 However, as this was an open-label, uncontrolled trial, it is impossible to assess how much of the improvement was due to a placebo effect
Here are some factors that can affect how quickly you notice results: Severity of Deficiency: Individuals with mild deficiencies may experience quick relief, but those with very low B12 levels might require several doses before a noticeable difference occurs
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While this isn't the same as drug approval, it does indicate a favorable safety profile based on toxicology data
Presented for research literature review only Tsang F et al
Sikiric et al., 2018
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