A Cochrane review comparing oral and intramuscular B12 found comparable effects on blood levels, and the same principle of good absorption applies to the subcutaneous route
That role is real and well described in biochemistry
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Methylcobalamin is the most expensive form of B12 however is favoured by Dr Knight due to its effectiveness with patients remotely and in clinic
The Best Time to Take a B12 Injection If you have a big event coming up, such as finals week, a vacation, or a wedding, you might be wondering about the best time to take a B12 shot to ensure you feel the benefits when you need them
That said, patients with active diabetes or significant metabolic dysfunction should have any investigational peptide protocol reviewed by their endocrinologist or primary care physician alongside their supervising aesthetic medicine provider