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Some individuals have genetic variations in glutathione synthesis genes (GCLC, GCLM, GSS) or detoxification enzymes (GST family) that may influence baseline capacity
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Individuals taking medication should discuss potential interactions with their healthcare practitioner
Researchers focused on direct oxidative stress reduction and detoxification tend to study Glutathione
The question of whether the increased cardiac workload (both rate and force) could cause long-term cardiac remodeling remains open
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