GLP-1 helps in glucose homeostasis by enhancing glucose-dependent insulin secretion from the pancreatic beta cells, inhibiting glucagon secretion, and delaying gastric emptying
"What may be happening, and we don't know for sure, is that when you stop them, your body's left in a GLP-1 deficit which has a major impact on the satiety signal going to the brain," says Whyte
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Diarrhoea, vomiting, constipation, and abdominal pain were also amongst the most frequently observed side effects
Some nausea is expected and usually peaks 24-48 hours after injection
Understanding receptor pharmacology helps researchers select the appropriate nasal spray format for their specific research focus