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Figure 1 Characteristics of included studies To ensure methodological clarity and appropriately weight the evidence, the included literature is organized into four distinct categories: completed head-to-head trials, contextual cardiovascular outcome trials, real-world observational studies, and ongoing (non-analytical) studies

With compounded GLP-1, each patients medication is prepared specifically for them, and drawn up in individual syringes

The medication can be administered into three approved sites: the abdomen, thigh, or upper arm

The initial metabolic shifts in microglia tend to trigger neuroinflammation and phagocytic suppression [65, 76]

No FDA status Not FDA-approved Compound AOD-9604 Mechanism Modified GH fragment

The physicians role is to evaluate whether the medication makes sense and how to use it safely