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10.1001/jama.2010.405 145 Pi-SunyerF
4L and Supplementary Fig
The way that melanocytes help is by the production of a dark pigment that is transferred to keratinocytes and forms a cap around the nucleus, like an umbrella, in hopes to protect their DNA from further damage and mutations
By contrast, cardiomyocytes isolated from vehicle-infused or AngII/PE-infused mice secreted relatively low concentrations of IGF-1, suggesting that myofibroblast-derived IGF-1 may be involved in agonist-induced cardiac fibrosis
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