The identification of these alternative immune checkpoints highlights the need for multi-targeted immunotherapeutic approaches that nanomedicine platforms are uniquely positioned to deliver ( Figure 1 )
A candidate genetic risk factor for vascular diseasea common mutation in methylenetetrahydrafolate reductase
Inspired by the nuclear envelope localization of zDHHC4, we engineered zDHHCs that ectopically target the ONM to detect mislocalized substrates
Reduced, oxidized and protein-bound forms of homocysteine and other aminothiols in plasma comprise the redox thiol status A possible element of the extracellular antioxidant defense system
In this session, we will focus on the polymorphisms in the gene encoding for MTHFR in schizophrenia (SZ), bipolar disorder (BPD), depression, autism disorder (ASD) and attention deficit hyperactivity disorder (ADHD)
Int J Biochem Cell Biol (2013) 45(5):93243