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Martin Holst Lange, executive vice president of development at Novo Nordisk, described REDEFINE 2 as confirming the superior efficacy of CagriSema in people with overweight or obesity and type 2 diabetes and expressed confidence in pursuing regulatory approval

One woman was bedridden, had a TSH of 100 IU/mL and antibodies over 1000 IU/mL, after attempting high doses of iodine for subclinical hypothyroidism that was mostly asymptomatic

CagriSema data additionally showed anti-inflammatory effects and significant blood pressure reductions in analyses presented at ObesityWeek, suggesting cardiovascular benefits that extend beyond weight loss alone

SOD administration also improved mean arterial pressure and reduced organ injury scores, particularly in the liver and kidneys (Zainumi et al., 2022)

doi:10.1097/SPV.0000000000000894 Lai HH, Vetter J, Song J, Andriole GL, Colditz GA, Sutcliffe S