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P53 phosphorylation at Ser15 was confirmed to enhance the affinity for both FOXO4 and FOXO4-DRI, providing a structural explanation for FOXO4-DRIs preferential engagement with the hyperphosphorylated p53 that characterises senescent cells
Peptides for women resources may provide additional context on female-specific considerations
Besides IF, other types of diet, including energy-restricted fasting and ketogenic diet (62), were also evaluated as nutrition therapy for MS (63)
Bacterial growth produces proteases that cleave the peptide backbone, lowering effective concentration and generating fragment impurities
10.1186/s13023-021-01693-9 Orphanet J Rare Dis
doi: 10.1038/s41419-018-1136-2 4
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