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Both remain classified as research compounds, and all published data comes from preclinical and animal studies rather than human clinical trials
Neuroimmunomodulation 21 (4), 183188 (2014)
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1) NAD+ Nicotinamide adenine dinucleotide, also known as NAD+, NAD plus or an NAD injection, is a coenzyme involved in energy metabolism and DNA support
Low levels of vitamin B12 can lead to: Depression Fatigue Poor memory Tingling sensation in the extremities Mania and psychosis (at extreme levels of deficiency) Permanent damage to the brain and nervous system (from long-term deficiency) Common causes of vitamin B12 deficiency include poor absorption (due to age, pernicious anemia, atrophic gastritis, Crohns Disease, long-term use of acid-reducing drugs, etc.) and vegetarian/vegan diets that limit the consumption of meat, dairy, and seafood
That it is the body's master antioxidant, that it is built from cysteine, glutamic acid, and glycine, that it supports detoxification and white-cell function these are textbook
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