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Description

Cardiovascular Protection GLP-1s have been shown to lower blood pressure, improve cholesterol profiles, and reduce inflammation in blood vessels

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Gastrointestinal side effects occur in 3045% of patients during dose escalation and require clinical oversight to adjust titration schedules and prevent discontinuation

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TGF- is secreted by AECs, endothelial cells, fibroblasts, myofibroblasts, and various immune cells, and it promotes EMT, metabolic reprogramming, and excessive ECM productionhallmark features of fibrosis [36, 37]

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Briefly, 900 L of citrated plasma was incubated with 100 L of samples (2575 g/mL) or heparin (control) at 37 C for 5 min in a Sysmex CA-560 coagulation analyzer (Japan)

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