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Signs of vitamin B12 deficiency include: Fatigue and weakness Nervous problems such as numbness or tingling Cognitive difficulties Megaloblastic anemia Heart palpitations Impaired vision B12 injection: Advantages over other forms of administration B12 injection: Advantages over other forms of administration Administering vitamin B12 by injection ensures maximum bioavailability, enabling this essential vitamin to reach the circulatory system and cells directly, without being degraded in the digestive system
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R., Han, J., Hardy, E
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A sample size of 54 subjects (14 normal renal function and ten in each of the four RI groups) was calculated to be sufficient for the primary objective of the study, with a power of 82% to show equivalence of exposure between subjects with severe RI and subjects with normal renal function
