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Alcohol may worsen gastrointestinal symptoms and should be limited during dose escalation phases

Standard 4-Step Escalation Schedule | Week Range | Dose | Clinical Decision Point | |---|---|---| | Weeks 1 to 4 | 2 mg SC once weekly | Assess nausea, vomiting, GI tolerability | | Weeks 5 to 8 | 4 mg SC once weekly | Hold if nausea grade 2 persists | | Weeks 9 to 12 | 8 mg SC once weekly | Check fasting glucose, LFTs at week 12 | | Weeks 13 to 24 | 12 mg SC once weekly (target) | Confirm tolerability before locking dose | Patients who cannot tolerate the step-up to 8 mg may remain at 4 mg for an additional 4 weeks before retrying escalation

Well discuss: Your health goals and concerns Current medications and supplements Medical history and lifestyle factors Expected outcomes and timeline Step 2: Baseline Lab Testing We perform comprehensive lab work to evaluate your current health status and ensure youre an ideal candidate for peptide therapy

The injections work by forcing your body to absorb more vitamin B12, causing your body to release more serotonin, which makes you feel good

Neuroscience (2014) 277:613

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