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Lastly, the results of a very recent systematic review and network meta-analysis aimed to compare the effects of oral antidiabetic drugs in endocrine and metabolic profiles in patients with PCOS confirmed that metformin was more beneficial in reducing serum total testosterone, whereas GLP-1RA + metformin reduced FAI more effectively [24]
Looking more closely at people living with diabetes, a recent meta analysis of 11 randomized controlled trials found that GLP-1s significantly reduced both cardiovascular and kidney events (such as kidney failure)
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