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1994, 266: R979-R988
Capodici, A., De Amicis, R., et al
Another warns you will regain weight
For healthcare leaders, biotech innovators, and strategy folks: this signals that the value proposition for GLP-1 therapies isnt solely weight loss or glycaemic control its anti-inflammation opens new therapeutic categories, pricing/benefit models, and organisational partnerships (endocrinology + immunology, metabolism + organ disease)
Agonism of GPR119 in both healthy or diabetic and obese mice, is known to improve glucose tolerance (90), or even prevent atherosclerosis in mice (332), while at the same time inducing the secretion of glucagon under low glucose levels avoiding hypoglycaemia (91)
It works best as part of a comprehensive program that includes nutritional guidance, physical activity, and ongoing support
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