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However, their translational relevance is restricted by the fact that congenital leptin deficiency (as seen in ob/ob mice) or leptin resistance (db/db mice) is extremely rare in humans (297299)
Hitting both at once can produce a synergistic pulse rather than two identical signals added together
NAD(+) metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus
Avoid administration during or immediately after intense exercise
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