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Vitamin B12 is used in the body in two forms, methylcobalamin and 5-deoxyadenosyl cobalamin

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One individual per group was euthanized before addressing the next animal in each group to render differences arising from the time of day at euthanization (e.g., cecal mass changes resulting from differences in time post-food consumption) comparable across all groups

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Since the first-line intervention for obesity is typically lifestyle change(s) 4 , this study purposefully combined LD switch with 5A-1MQ treatment

Reunanen, J