Similarly, ophthalmological endpoints were investigated adjusting for (1) papilledema degree, (2) pRNFL thickness, (3) GCL volume, or (3) ONSD at baseline as appropriate and in a second step also for weight loss to evaluate potential independent treatment effects of GLP-1-RAs
(3) Serum IGF-1 and IGF-BP-3
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Polygenic Determinants of Severe Hypertriglyceridemia. Human Molecular Genetics, vol
Twice-weekly to daily measurements during titration Clinic visits every 4-8 weeks during titration for patients on multiple antihypertensives Less intensive monitoring once weight loss has stabilized and antihypertensive regimen has been adjusted Re-evaluation if symptoms emerge (lightheadedness, fatigue out of proportion to weight loss, syncope) Patients without hypertension and not on antihypertensive medications generally do not need intensive BP monitoring
Instead, it may: Reduce excessive inflammation Allow normal early healing inflammation Prevent inflammation from lingering too long Think of it as turning down the volume, not muting the sound