Long-Term Benefits (8+ Weeks) After about two months of consistent use, you can expect firmer, more lifted skin with a noticeable reduction in sagging and deeper wrinkles
Mol Psychiatry 26:54815503
PubMed Central , If you'd like to read this study yourself: If you'd like to read this study yourself: If you'd like to read this study yourself: 4 Malaguarnera, Mariano, et al
Read More AAD 2026: The Compounding Conversations Every Dermatology Prescriber Should Be Having As thousands of dermatologists, residents, and prescribers gather in Denver for the American Academy of Dermatologys 2026 Annual Meeting, the scientific sessions will cover the usual spectrum: biologics for atopic dermatitis, checkpoint inhibitor dermatology, advances in melanoma imaging, new approaches to acne scarring
Some users ask about taking injections early or adjusting their schedule to align with medication supply logistics
Less common side effects included skin tingling and a temporary increase in heart rate during the first 24 weeks of treatment