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This is not specific to retatrutide but occurs with any aggressive caloric deficit or weight loss intervention
Rarely, hypersensitivity reactions can occur, for instance, urticaria (hives) or other allergic-type reactions have been reported in isolated cases
If specialist advice is not immediately available, consider the following: Initial treatment : IM hydroxocobalamin 1 mg once daily on alternate days until no further improvement
21) reports +23% at 70 kg and 21% at 120 kg the heavy-end figures disagree between the sponsor paper and the regulator, so treat the low-weight direction as well established and the magnitude at high weight as uncertain
Your healthcare provider might recommend B12 supplementation if you are on these medications to prevent deficiency