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But the mechanism is well-characterized and the target (NNMT in adipose tissue) is a legitimate pathway for visceral fat reduction

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Too much B12: Signs, causes, and how to manage it

Researchers commonly utilize 5-Amino-1MQ in experimental models examining metabolic adaptation, nutrient partitioning pathways, cellular energy expenditure, and enzyme-mediated metabolic regulation

Unless the argument is that those people can access their B12 stores and you cannot, but I don't think we can assume that

Fortified foods: Numerous breakfast cereals, plant-based milks, and nutritional yeast are fortified with B12