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If they inject it into a vein, the body may lose a high proportion as the person passes urine
Expect body-composition shifts over months, not dramatic weight loss
Consistency is also key
Moreover, LC administrated for 2 weeks suppresses atrogin-1 messenger RNA (mRNA) level in suspended rats hindlimb [35], and only 7 days of LC administration downregulates MuRF-1 and atrogin-1 mRNAs reducing muscle wasting in a rat model of cancer cachexia [32]
However, given that orforglipron will be a prescription medication, physicians could potentially prescribe it off-label for diabetes prior to formal diabetes approval, a common practice in the GLP-1 space
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