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[8] Cagrilintide, by contrast, is not approved for any indication anywhere

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References [1] Sikiric, P., et al

GPx isoenzymes are all antioxidant enzymes that reduce potentially damaging reactive oxygen species (ROS), such as hydrogen peroxide and lipid hydroperoxides, to harmless products like water and alcohols by coupling their reduction with the oxidation of glutathione (Figure 2a )

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Two Phase 3, randomized, double-blind, placebo-controlled trials enrolled 816 patients and measured visceral fat by CT scan