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While that study focused on phenotypic characterization, we further investigated the molecular mechanism of TEX44 function

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485,486 This affects the synthesis of triacylglycerol (TAG), phosphatidic acid (di-P PA), and diacylglycerol (DAG) in the liver

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Separately, TRANSCEND-T2D-1 part of a distinct three-trial diabetes-specific program confirmed -2.0% HbA1c reduction and 16.8% weight loss in 537 type 2 diabetes patients (topline March 2026, published in The Lancet, June 2026)

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