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The therapeutic approach for HCC remains focused on curative treatments for early stages (resection, ablation, transplantation) or palliative systemic therapies for advanced disease (tyrosine kinase inhibitors [TKIs] and VEGF inhibitors) and immunotherapies (i.e., programmed death 1 [PD-1]/programmed cell death-ligand 1 [PD-L1] inhibitors and anti-cytotoxic T-lymphocyte-associated protein 4 [CTLA-4] antibodies) (Sadagopan et al., 2024

Key takeaways Ozempic constipation may occur because Ozempic can slow digestion, reduce gut motility, and decrease thirst which can lead to not drinking enough water

One study found that 20% of Hashimotos disease patients have gastric autoimmunity, including pernicious anemia

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Metabolic Support: Semaglutide is a GLP-1 receptor agonist that helps regulate blood sugar levels, improve insulin sensitivity, and promote weight loss by reducing appetite and enhancing satiety signals in the brain

Genes Dev 27:234250 Feige JN, Lagouge M, Canto C et al (2008) Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation