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Severe hypotension, exacerbation of angina on initiation (rare), gingival hyperplasia with long-term use
Overall reduced focus on food
GLP-1 receptor agonism potentiates glucose-dependent insulin secretion and signals through hypothalamic circuits governing food intake
Also observed in the obese mice were increased mRNA levels of Xbp-1, Grp78 and CHOP, as these are indicators of endoplasmic reticulum stress, and are believed to be activated by obesity
Supports detoxification
Research applications must follow institutional review protocols
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