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Trial SELECT (Lincoff et al., NEJM 2023) Design Phase 3 / 39.8 mo mean follow-up Population 17,604 adults with CVD + overweight or obesity, no diabetes Key result 20% reduction in major heart events (HR 0.80
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In addition, GLP-RA use was associated with significantly reduced risks for all-cause mortality, hospital admissions due to infections, and admissions due to any cause in both BMI groups compared with DPP-4 inhibitor use
If they find it hard to wind down, try a mindfulness exercise
Why This Matters Recognizing this overlap matters for two reasons: Clinical Communication
Lee and Lee, 2010
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