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Corts L, Domnguez M, Simn MA
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No human safety data exists
Furthermore, L-carnitine upregulates genes involved in fatty acid transport and mitochondrial -oxidation ( Octn2, Cpt1a, Cpt2, Acadm ) while increasing metabolites associated with TCA cycle, urea cycle, and antioxidant pathways (malate, citrulline) (45)
But the drug hit a supply shortage in late 2021 due to manufacturing issues, which the manufacturer managed to fix in the second half of 2022
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