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Hyperglycemic conditions and the resultant metabolic disorder primarily disrupt autophagy by blocking autophagic flux and compromising lysosomal function, ultimately leading to stagnation of the autophagy pathway (146, 147)
AMPK, AMP-Activated Protein Kinase
Glutathione can also be taken as an inhaled form in a nebulizer
Liposomal glutathione circumvents this by encapsulating the molecule in phospholipid vesicles, with pilot data showing 25-40% plasma increases within two weeks
10.1038/s41392-021-00687-0 Signal Transduct Target Ther
Kwon, T
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