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35 Case presentation A 51-year-old woman known to have bipolar affective disorder presented to the emergency department (ED) having overdosed on 120 tablets of VPA (Depakene) 30 minutes prior to her arrival
Source: Arrone, et al New England J of Medicine May 11, 2025 Researchers randomized about 1,500 people with obesity and without diabetes to be treated with either tirzepatide or semaglutide, both at the highest tolerable recommended doses, and followed them for 72 weeks
The medication's effect on satiety and food intake diminishes over time, which may lead to increased hunger and potential weight regain
Biochem J, 2005
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