Primary care physicians will likely need education and training focused on this new class of medications, given a shortage of endocrinologists and obesity medicine specialists. Lee and colleagues noted there were study limitations, such as a lack of data on prescription indication, including whether it was used off-label. However, the increase in dispensing of injectable semaglutide for weight management suggests increasing use for this indication, they wrote
The medication works by enhancing insulin secretion in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying
SaranRRobinsonBAbbottKCBragg-GreshamJChenXGipsonDet al
Always follow clinical instructions carefully
Blonde L, Russell-Jones D: The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: an overview of the LEAD 15 studies
So, we have this immediate response thats impactful for diabetes