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Arachidonic acid is primarily metabolized via two pathways: the cyclooxygenase (COX) pathway and the lipoxygenase (LOX) pathway
References Janeway, C
Methionine is important for Phase II detoxification (it supports the sulfation pathway) and helps with the absorption of two vital thyroid nutrients, selenium, and zinc
Many anecdotal protocols range between 2001000 mcg per day, but individual needs differ
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