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Evidence on B12 Supplementation During GLP-1 Therapy Clinical trials of semaglutide for weight loss (the STEP trials with over 4,500 participants) did not routinely pair semaglutide with B12 injections or measure specific B12 supplementation outcomes
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We often recommend looking at compounded options, such as our lipotropic injections, to help support patient metabolism during this transition
Exenatide-PD3, reported in The Lancet in early 2025, was the largest and longest trial of a GLP-1R agonist in Parkinsons disease: 194 patients, once-weekly exenatide, 96 weeks
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