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This is significant because 90% of the bodys serotonin is produced in the gut
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A meta-analysis reported a modest positive effect of vitamin D supplementation on muscle strength in elderly individuals with deficiency, but no effect on muscle mass, nor on muscle preservation during caloric restriction [57, 58]
Repeated dosing studies in rats, dogs, and mice for up to 6 weeks across doses from 0.006 mg/kg to 20 mg/kg via multiple routes showed excellent tolerance
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PMID: 18172170, DOI: 10.1056/nejmoa0706467
