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Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration

Several studies have reported the beneficial effects of SiNPs on alleviating As toxicity in plants by reducing As uptake and translocation, increasing As sequestration and detoxification, modulating physiological and biochemical responses, and enhancing antioxidant defense mechanisms 11

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Proline and betaine protect enzymes against heat inactivation