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Semaglutide, the GLP-1 agonist behind Ozempic and Wegovy, is the most direct comparator to tirzepatide

Importantly, in the same paper the anti-obesity efficacy experiment in diet-induced obese mice was carried out by systemic administration of the inhibitor the researchers did not report an oral-gavage efficacy arm

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When intake is in play, the relevant details are the form, the dose per serving, how often the patient takes it, how long they have been taking it, and how recently