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The clinical course was correlated with magnetic resonance imaging and multimodal evoked potential findings, but not with ammonia levels

More significant results like enhanced lean muscle mass, reduced body fat, and elevated natural growth hormone (HGH) levels typically emerge gradually over three to six months

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For optimal results, most regimens incorporate measures such as sleep optimization, increased movement, and nutrition modifications

PBMCs were purified from other blood components and the ficoll histopaque by washing twice with 1x phosphate-buffered saline (PBS)

Novo Nordisk NDA filed December 2025