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Receptor engagement initiates Gs-mediated adenylyl cyclase activation and intracellular cAMP elevation in somatotroph cell models, triggering pulsatile growth hormone (GH) release

These variations may reduce GLP-1 secretion in the gut or make the pancreas less responsive to its signals

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Goldman JG, Williams-Gray C, Barker RA, Duda JE, Galvin JE

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