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Tapering and discontinuation considerations
Richfield et al
[9] GST-Pi is expressed in many human tissues, particularly in the biliary tree, renal distal convoluted tubules and lungs
Injection site reactions (15-25%), occasional nausea (5-10%), and rare dizziness (3-7%) are the most commonly reported issues, and these typically resolve within hours to days without treatment
Mice were euthanized on the last day of treatment
Disruptions to the synthesis, recycling, or cellular distribution of GSH are prominent observations that exist in multiple neurodegenerative diseases, suggesting a possible route of therapeutics that could facilitate treatment of these conditions
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