Greig NH, Mattson MP, Perry T, Chan SL, Giordano T, Sambamurti K, Rogers JT, Ovadia H, Lahiri DK (2004) New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-alpha inhibitors, and GLP-1 receptor agonists
Efficacy of once-weekly semaglutide versus placebo as adjunct to basal insulin in type 2 diabetes (SUSTAIN 9): a randomised, placebo-controlled trial
In this subcluster, we observed activation of the transcription factor ARX
Cardiovascular effects: Some patients experience modest reductions in blood pressure whilst taking GLP-1 receptor agonists, which is generally beneficial for cardiovascular health but can occasionally cause postural hypotension or light-headedness, particularly in individuals already taking antihypertensive medications
A recent systematic review stressed the need for larger, longer trials before drawing final conclusions
doi:10.1111/jnc.15105 pmid:32578216 Mazzucco CA, Lieblich SE, Bingham BI, Williamson MA, Viau V, Galea LAM (2006) Both estrogen receptor and estrogen receptor agonists enhance cell proliferation in the dentate gyrus of adult female rats