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Many studies revealed the existence of several miRNAs able to target NFE2L2 , resulting in NFE2L2 mRNA degradation and inhibition of NRF2 protein translation, such as miR-144, miR-28, miR-93, miR-153, miR-27a, miR142-5p, and miR-34
Likewise, high-performance athletes burn through carnitine reserves faster than average due to elevated metabolic demands
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When 5GABA-A receptor PAM, MP-III-022 was used in rats in the VPA model, an increase in mRNA level of KCC2 was observed only in females treated with a dose of 1 mg/kg, while the mRNA level of Gabra5 and Nkcc1 remained unchanged across doses and animal sexes [58]
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