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Immunoblotting was performed with the following primary antibodies: anti-GPX4 (Abcam, catalog ab125066, 1:3000), anti-ACSL4 (Santa Cruz, catalog sc-365230, 1:1000), anti-LPCAT3 (Abcam, catalog ab232958, 1:500), anti-fibronectin (Abcam, catalog ab45688, 1:5000), anti-collagen-I (Proteintech, catalog 14695-1-AP, 1:1000), and anti--SMA (Abcam, catalog ab124964, 1:2000)

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Several garlic-derived organosulfur compounds, including S-allylcysteine and ajoene, have been found to inhibit 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase), a critical enzyme in the cholesterol biosynthesis pathway (39, 40)

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