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HDL cholesterol may initially decrease during active weight loss but generally increases with weight maintenance

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Transmission electron microscopy has also shown that pregnant women with PCOS have reduced mitochondrial volume, concentrated mitochondrial membrane density, no mitochondrial ridge, and ruptured mitochondrial outer membrane (key characteristics of mitochondrial morphological changes during ferroptosis)

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However, a gastric pH of above 3.8, seen in PPI users, showed significant bacterial overgrowth of the small intestine (Theisen 2000)