As much as we may want a quick fix for the rising levels of obesity seen around the world, Powell-Wiley says, its important to understand that this isnt the panacea. We still dont know how well semaglutide works in a diverse group of people, she says
With the growth and availability of compounded GLP-1s, overdoses and calls to poison control centers have spiked in the United States
Microdosing keeps the dose low and steady instead
GLP-1 Drugs: A Complete History of Incretin-Based Therapy Learn the complete history of GLP-1 drugs from the incretin effect to 2026 breakthroughs
The good news is they result in an average weight loss of 515% of body weight
Just based on two high level metrics when it was removed from the shortage list (based on pharmacy supply calls and patients pick up rates here at Ro): Pharmacy Supply Calls: 38% of pharmacies have stock 15% do not have stock but expect to have it in the future 48% say its on back order and materially less supply than other Wegovy doses Patient pick up rates: 30-35% are able to find supply in 14 days 65-70% are able to find supply in 30 days If providers are using the FDAs list to determine what path to recommend for their patients, we need to ensure the FDA has as much information as possible to make that determination